Research Area

Functional Genomics, Evolutionary Biology, Bioinformatics. (See https://gxelab.github.io/ for more)

Contact Information

E-mail: hong_zhang@lzu.edu.cn

Address: Room 104A, Xiuyun Building

Education

2014.09-2019.07    Ph.D. (Bioinformatics), Peking University

2010.09-2014.07    B.Sc. (Biology), Peking University

Work Experience

2021.06-Present     Professor, Lanzhou University

2019.07-2021.06    Postdoctoral fellow, Peking University

Publications

(# means co-first author; * means co-corresponding author)

1. H. Zhang, Y. Wang, X. Wu, X. Tang, C. Wu, and J. Lu, Determinants of genome-wide distribution and evolution of uORFs in eukaryotes. Nature Communications. 12, 1076 (2021). doi: 10.1038/s41467-021-21394-y
2. H. Zhang^#, Y. Wang^#, X. Tang, S. Dou, Y. Sun, Q. Zhang and J. Lu. Combinatorial regulation of gene expression by uORFs and microRNAs in Drosophila. Science Bulletin. 2020, doi: 10.1016/j.scib.2020.10.012
3. S. Luo^#, H. Zhang^#, Y. Duan^#, X. Yao, A.G. Clark^* and J. Lu^*. The evolutionary arms race between transposable elements and piRNAs in Drosophila melanogaster. BMC Evol. Biol. 2020, 20: 14.
4. H. Zhang^#, Y. Wang^# and J. Lu. Function and evolution of upstream ORFs in eukaryotes. Trends in Biochemical Sciences. 2019, doi: 10.1016/j.tibs.2019.03.002.
5. Y. Wang^#, H. Zhang^# and J. Lu*. Recent advances in ribosome profiling for deciphering translational regulation. Methods. 2019, doi: 10.1016/j.ymeth.2019.05.011.
6. H. Zhang^#, Y. Wang^#, J. Li, H. Chen, X. He, H. Zhang, H. Liang^* and J. Lu^*. Biosynthetic energy cost for amino acids decreases in cancer evolution. Nature Communications. 2018, 9: 4124.
7. H. Zhang^#, S. Dou^#, F. He, J. Luo, L. Wei and J. Lu. Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development. PLoS Biology. 2018, 16: e2003903.
8. Y. Duan^#, S. Dou^#, H. Zhang^#, C. Wu, M. Wu and J. Lu. Linkage of A-to-I RNA Editing in Metazoans and the Impact on Genome Evolution. Molecular Biology and Evolution. 2018, 35: 132-148.
9. Y. Duan^#, S. Dou^#, S. Luo^#, H. Zhang and J. Lu. Adaptation of A-to-I RNA editing in Drosophila. PLoS Genetics. 2017, 13: e1006648.
10. Y. Wang, J. Luo, H. Zhang and J. Lu. microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes. Molecular Biology and Evolution. 2016, 33: 2232-2247.

Funding

Young Scientists Fund of NSFC (2023-2025)

Fundamental Research Funds for the Central Universities (2022-2024)

Research startup package of Lanzhou University (2021-2026)

Innovative Talents Supporting Program of Chinese Postdoctoral foundation (2019-2021)

Honors & Awards

2019      Boya Postdoctoral fellowship, Peking University

2018      National Scholarship, Ministry of Education of China

2017      Presidential Scholarship, Peking University